Commissioning &
Qualification

Proof your facility does what you claim

Why CQV Matters

An Unqualified System Is a Finding Waiting for an Inspector.

Every clean room, autoclave, bioreactor, water system, and line in your facility carries an unspoken claim: that it does what your batch record says it does. Commissioning, qualification, and validation are how that claim is proven, on paper an auditor will accept. Done as box-ticking, CQV generates binders nobody trusts and delays that nobody planned. Done as a science- and risk-based program under ASTM E2500, it verifies what actually matters to product quality and gets your facility making product on schedule.

The Qualification V-Model

Every Requirement, Traced to the Test That Proves It.

CQV is a chain of traceability. What you specify on the way down has to be verified on the way back up. When that linkage is clean, qualification is fast and defensible. When it's broken, you find out during an inspection.

Specify
User Requirements (URS)
What the system must do for the process.
Verify
Performance Qualification (PQ)
Proves it performs under real production conditions.
Specify
Functional Specification (FS)
How the system is meant to function.
Verify
Operational Qualification (OQ)
Proves it operates across its full range.
Specify
Design Specification (DS)
How the system is built and configured.
Verify
Installation Qualification (IQ)
Proves it was installed as designed.
Build & Commission
Design Review · FAT · SAT
Left arm: define the system Right arm: prove the system

A facility or system that needs to be qualified against a hard start-up date?

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The CQV Lifecycle

From Empty Room to Validated State.

We run the full arc, or step in at whichever phase your project has reached, without making you re-do the work already done well.

Commission

FAT, SAT, and system walkdowns that catch installation and function problems before qualification ever begins.

Qualify

IQ, OQ, and PQ protocols authored, executed, and closed, each traced to the requirement it exists to prove.

Validate

Process validation and PPQ that demonstrate the process makes conforming product, batch after batch.

Sustain

Requalification schedules, periodic review, and continued process verification that keep the validated state validated.

What We Qualify

Every System That Touches the Product.

From a single autoclave to an entire new facility, we qualify the systems regulators expect to see under control, on a risk basis that puts the effort where product quality actually lives.

Facilities & Clean Rooms

New builds, expansions, and clean room classification, qualified from URS through PQ against ISO 14644 and GMP grade requirements.

Utilities & HVAC

Water for injection, clean steam, compressed gases, and HVAC, qualified for the critical quality attributes they feed into the process.

Process Equipment

Bioreactors, fillers, lyophilizers, autoclaves, and skids, qualified across their operating ranges and integrated into the process.

Computerized Systems

CSV under GAMP 5 and 21 CFR Part 11: automation, historians, and lab systems validated for data integrity, not just function.

Process Validation

Process performance qualification and continued process verification, from protocol design through the campaign that proves consistency.

Remediation & Gap Closure

Stalled, failed, or legacy qualifications assessed and brought current, so an old gap doesn't become the finding in your next inspection.

Operating Standards

What Disciplined CQV Looks Like.

We don't publish vanity metrics. We run to standards, and we put them in writing at the start of every engagement.

Risk decides the effort.

Under ASTM E2500, verification concentrates on what affects product quality and patient safety. We don't qualify a light switch to the same depth as a sterilizer.

Traceable, end to end.

Every acceptance criterion traces to a requirement, and every requirement to a test. A reviewer can follow the thread from URS to executed protocol without a gap.

Written to survive execution.

Protocols are authored so the person executing them can't reasonably misread a step. Deviations come from reality, not from ambiguous instructions.

Qualified stays qualified.

We hand over a requalification and periodic review plan, so the validated state is maintained deliberately rather than rediscovered during an audit.

Who You're Working With

People Who Have Executed on the Floor.

Our CQV leads have authored the protocols, run the executions, and closed the deviations on real start-ups under real schedule pressure. You aren't being staffed with junior consultants under a partner's name; you get the senior practitioner on every call.

Protocol-to-Floor Experience

Leads who have written IQ/OQ/PQ protocols and then executed them on the equipment, so the documents match how the systems actually behave.

Senior-Only Engagement Model

The lead consultant on your engagement is the one doing the work. We don't bait-and-switch with junior staff after the contract is signed.

Risk-Based by Practice

ASTM E2500 and ISPE Baseline fluency applied for real, focusing effort where quality risk lives instead of qualifying everything equally.

Start-Up Schedule Fluency

Practitioners who have carried facilities and systems to a validated state against fixed launch dates, and who plan CQV as a critical-path program.

Work With Us

Ready to Get to a Validated State on Schedule?

Tell us what you're bringing online and when it has to make product. We'll match you with a senior CQV lead and respond within one business day. All inquiries are strictly confidential.

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